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e attenuated severity of acute GVHD in animal models. Within our knowledge, little is known about the pathobiological roles of AP-1 signaling in GVHD development. Although acute GVHD is considered to be mediated mainly by donor T cells, recent animal studies suggest that B cells might also play an important role in the biology of GVHD [46]. The specific mechanisms of B cells involved in the develo
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e attenuated severity of acute GVHD in animal models. Within our knowledge, little is known about the pathobiological roles of AP-1 signaling in GVHD development. Although acute GVHD is considered to be mediated mainly by donor T cells, recent animal studies suggest that B cells might also play an important role in the biology of GVHD [46]. The specific mechanisms of B cells involved in the develo
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